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Job Title: Biochemist - II (Associate)
Category:  Professional & Business Operations
  • The Protein Science group enables HTS, assay development, crystallography and biologics discovery by providing high quality, well characterized recombinant proteins.
  • The incumbent will be involved in cloning, expression, purification and characterization of recombinant proteins to support various drug discovery activities.
  • The primary duties of the position will be purification and characterization of various recombinant protein targets.

Summary of essential job functions:
• Protein purification utilizing IMAC, ion exchange, affinity and size exclusion chromatography
• Microbial expression of recombinant proteins using bioreactor and/or shake flask up to 10L scale
• Protein characterization including but not limited to: SDS-PAGE, western blot, protein concentration, LC-Mass Spec and dynamic light scattering
• Presentation of data at internal scientific meetings 

  • Qualifications include a BS/MS with 2-5 years of laboratory experience or Ph. D with 0-2 years of laboratory experience in Biochemistry, Molecular Biology, Chemistry or related science.

  • Candidate with strong purification skills including chromatography and protein characterization is required.

  • Experience with membrane protein purification, microbial cell culture and AKTA (or equivalent) systems is strongly desired.

  • Experience in design of DNA constructs using standard software tools is a plus.

  • The individual should be highly motivated and be able to work in a goal-oriented, deadline driven environment.

  • Excellent communication and inter-personal skills are essential. 

Location  North Wales , PA
Minimum Experience (yrs):  2+
Required Education:  Not Specified

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